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The study aims at measuring the sensitivity and specificity of a series of imaging signs (recorded by magnetic resonance angiography, vascular tomodensitometry, vascular ultrasonography, retina angiography and retina optic coherence tomography) for the diagnosis of Horton disease, the gold standard being the result of temporal artery biopsy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cases | Patients admitted to a tertiary hospital, with a clinical suspicion of Horton disease |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vascular tomodensitometry | Radiation |
| ||
| Magnetic resonance angiography |
| Measure | Description | Time Frame |
|---|---|---|
| MRI angiography mural inflammation | Presence of signs of artery mural inflammation in T1 sequence of MRI angiography | Baseline |
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Inclusion Criteria:
Major criteria : Age > 50 ans ; headache ; intermittent jaw or tongue pain ; visual impairment ; ESR > 50 mm at 1h and/or CRP > 8mg/l.
Minor criteria: temporal artery or scalp tenderness ; facial pain or tenderness ; fever >38°C, weight loss >10%, anorexia, fatigue.
Exclusion Criteria:
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Patients admitted to the Fondation Ophtalmologique Adolphe de Rothschild with a suspected Horton disease
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondation Ophtalmologique A. de Rotchschild | Paris | 75019 | France |
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| Other |
|
| Vascular ultrasonography | Other |
|
| Retinal angiography | Other |
|
| Retinal optical coherence tomography | Other |
|
| ID | Term |
|---|---|
| D013700 | Giant Cell Arteritis |
| ID | Term |
|---|---|
| D020293 | Vasculitis, Central Nervous System |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001167 | Arteritis |
| D014657 | Vasculitis |
| D017445 | Skin Diseases, Vascular |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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