Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms

Evaluation of Effects of Fermented Dairy Products Containing Probiotics Alone or in Association With Fibers on Bowel Functions, Constipation Symptoms and Health Related Quality of Life in Adult Subjects With Moderate Constipation: an Exploratory Randomized Double-blind, Controlled Adaptive Study

First experimental study (Proof Of Concept) to investigate bowel function parameters on which a fermented milk product with probiotics alone or in association with fibers has a potential effect.

Main eligibility criteria (non-exhaustive list) are defined as:

• Healthy Caucasian subject of both gender, aged from 18 to 69 years
• Subject with body mass index (BMI) between 18 kg/m2 (bound included) and 30 kg/m2 (bound excluded)
• Subjects with moderate constipation defined according to ROME III adapted criteria.
• Subjects without ongoing or diagnosed gastrointestinal disease or complications.
• Subjects without previous (within one month), ongoing or planned therapy during the study with drugs altering bowel function.
• Subjects without known gluten intolerance, lactose intolerance or allergy to milk proteins.