Intraoperative Ketamine and Magnesium Therapy for Control of Postoperative Pain After a Liposuction and Lipoabdominoplasty

Efficacy of Ketamine and Magnesium Association in the Postoperative Pain After Liposuction and Lipoabdominoplasty: Prospective, Randomized and Blinded Study

Lipoabdominoplasty and liposuction are one of the most common plastic surgeries. The management of postoperative pain is complex. Non Steroidal Anti Inflammatory Drugs (NSAIDs) are insufficient, while opioids are avoided by their adverse effects and regional techniques are hampered by a premature discharge. In this context, the investigators seek an intraoperative multimodal analgesic technique blocking NMDA receptors with ketamine plus magnesium to significantly decrease postoperative pain.

Inclusion Criteria:

• Female and male
• 18 years or older
• Liposuction and lipoabdominoplasty
• ASA 1 and 2
• BMI 21-28 Kg/m2
• Full secondary education

Exclusion Criteria:

• Patients with surgeries added to the main proceedings
• Scheduled to tuck in Flor de Lis or Body Lift
• History of use of analgesic drugs 48 hours before surgery
• Peripheral central neurological diseases
• Known allergy will be excluded to medication in use in this study (ketamine, magnesium, clindamycin and penicillin or other)