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The purpose of the protocol is to evaluate and describe QoL, in the population of Polish acromegalic patients treated with Lanreotide Autogel® 120 mg during the 24 months (long term observation).
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| Measure | Description | Time Frame |
|---|---|---|
| Acromegaly quality of life (AcroQol) questionnaire | The AcroQol questionnaire and total AcroQol score will be analysed descriptively overall and according to hormonal control, presence of prior radiotherapy, presence of prior surgery. | Change from baseline (visit 1), visit 3 and 6 (visits occur approximately every 4-5 months, during 2 years of observation) |
| Measure | Description | Time Frame |
|---|---|---|
| Hormonal control of serum growth hormone (GH) and insulin-like growth factor 1 (IGF-1) concentration | Descriptive analysis | Visit 1 to 6 (visits occur approximately every 4-5 months, during 2 years of observation) |
| Clinical symptoms of acromegaly |
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Inclusion Criteria:
Exclusion Criteria:
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Specialist care clinic and hospital clinic.
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| Name | Affiliation | Role |
|---|---|---|
| Ipsen Medical Director | Ipsen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bialystok | Poland | |||||
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| ID | Term |
|---|---|
| D000172 | Acromegaly |
| ID | Term |
|---|---|
| D001849 | Bone Diseases, Endocrine |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D006964 | Hyperpituitarism |
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Descriptive analysis of the following symptoms - Headache, Sweating, Joint symptoms and Swelling
| Visit 1 to 6 (visits occur approximately every 4-5 months, during 2 years of observation) |
| Patient overall assessment of satisfaction from treatment | Using a Likert scale (from 1 to 5); completely satisfied, rather satisfied, neither satisfied nor dissatisfied, rather dissatisfied, completely dissatisfied. | Visit 1 to 6 (visits occur approximately every 4-5 months, during 2 years of observation) |
| Lanreotide injection interval (28, 42 or 56 days) | Summary of overall and by hormone control status. | Visit 1 to 6 (visits occur approximately every 4-5 months, during 2 years of observation) |
| Bydgoszcz |
| Poland |
| Bytom | Poland |
| Gdansk | Poland |
| Gliwice | Poland |
| Katowice | Poland |
| Kielce | Poland |
| Krakow | Poland |
| Lodz | Poland |
| Lublin | Poland |
| Olsztyn | Poland |
| Opole | Poland |
| Poznan | Poland |
| Rybnik | Poland |
| Rzeszów | Poland |
| Szczecin | Poland |
| Warsaw | Poland |
| Wroclaw | Poland |
| D010900 |
| Pituitary Diseases |
| D007027 | Hypothalamic Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D004700 | Endocrine System Diseases |