The purpose of this study is to assess the efficacy, safety and patient acceptability of Somatuline Autogel in patients with acromegaly previously treated with octreotide LAR.

Inclusion Criteria:

• Clinical diagnosis of acromegaly
• The patient must have been tested at Week -4 (4 weeks prior to the Baseline visit) and shown to have a GH level <10 mU/L.
• The patient must have been treated with a stable dose of octreotide LAR for at least four months prior to study entry
• Life expectancy of at least 2 years

Exclusion Criteria:

• Adenectomy within past 6 months, or likely during study period
• Radiotherapy for acromegalic disease within 1 year, or likely during study period
• Unstable concomitant dopamine agonist therapy