The purpose of the protocol, is to evaluate if lanreotide Autogel 120 mg is effective in the control of Growth Hormone (GH) secretion in patients with active acromegaly.

Inclusion Criteria:

• Documented diagnosis of active acromegaly, defined by serum GH levels above 5 µg/L, absence of reduction of serum GH levels below 1µg/L after oral glucose tolerance test (OGTT) and abnormal IGF-1 values

Exclusion Criteria:

• Patients who have undergone pituitary surgery less than 3 months before selection
• Patients previously treated with radiotherapy
• Patients previously treated with somatostatin analogue except for a pre-surgical treatment not longer than 3 months