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Investigation of Clinical Effect of Platelet Rich Plasma Combined With Laser on Acne Scar
Platelet Rich Plasma may relieve the adverse effect of laser treatment. and it can be expected to improve acne treatment result.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fractional CO2 laser with PRP | Experimental | fractional carbon dioxide laser followed by intradermal injection of platelet rich plasma |
|
| fractional CO2 laser with NS | Active Comparator | fractional carbon dioxide laser followed by intradermal injection of NS |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fractional carbon dioxide laser with platelet rich plasma | Procedure | fractional carbon dioxide laser followed by platelet rich plasma injection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Global assessment of acne scar | 5-point grading of acne scar | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| ECCA (échelle d'évaluation clinique des cicatrices d'acné) | quantitative analysis of acne scar | 12 weeks |
| adverse effect assessment | adverse effect assessment - erythema index, Epithelization Scale (0-12 point) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dae Hun Suh, PhD | Department of Dermatology, Seoul National University College of Medicine | Study Chair |
| Seonguk Min, Msc | Department of Dermatology, Seoul National University College of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Dermatology, Seoul National University College of Medicine | Seoul | 110-744 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21276157 | Background | Tierney EP, Eisen RF, Hanke CW. Fractionated CO2 laser skin rejuvenation. Dermatol Ther. 2011 Jan-Feb;24(1):41-53. doi: 10.1111/j.1529-8019.2010.01377.x. |
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| ID | Term |
|---|---|
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |
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|
| fractional carbon dioxide laser with NS | Procedure | fractional carbon dioxide laser followed by normal saline injection |
|
|
| 12 weeks |