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Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Clean Cookstove | Active Comparator | Subjects will use ethanol stoves using bioethanol |
|
| Traditional Cookstove | Other | Subjects will use traditional firewood or kerosine cookstove and receive education on how to reduce air pollution exposures |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clean Cookstove | Other | Ethanol |
| |
| Traditional Cookstove |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse Pregnancy Outcomes | (first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births. | At birth |
| Measure | Description | Time Frame |
|---|---|---|
| Reduction in personal exposure to PM2.5, CO and PAH | Reduction in personal exposure to PM2.5, CO and PAH in the Ethanol intervention group relative to the control (kerosene/firewood) group | At birth |
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Inclusion Criteria:
Exclusion Criteria:
Smoking women or women with smoking family members
Women with a high-risk pregnancy defined as:
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| Name | Affiliation | Role |
|---|---|---|
| Christopher Olopade, MD | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| College of Medicine. University of lbadan, Ibadan | Ibadan | Nigeria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35901049 | Derived | Deji-Abiodun O, Adedokun B, Alexander D, Dutta A, Ibigbami T, Olamijulo J, Adepoju D, Adekunle S, Ojengbede O, Olopade CO. Impact of prenatal maternal psychological distress on fetal biometric parameters in household air pollution-exposed Nigerian women. PLoS One. 2022 Jul 28;17(7):e0272053. doi: 10.1371/journal.pone.0272053. eCollection 2022. | |
| 34187482 |
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| Other |
Firewood / Kerosene |
|
| Dutta A, Alexander D, Karrison T, Morhasson-Bello O, Wilson N, Atalabi OM, Adu D, Ibigbami T, Adekunle S, Adepoju D, Olamijulo J, Akinwunmi O, Afolabi OS, Deji-Abiodun O, Adedokun B, Aschebrook-Kilfoy B, Ojengbede O, Olopade CO. Household air pollution, ultrasound measurement, fetal biometric parameters and intrauterine growth restriction. Environ Health. 2021 Jun 23;20(1):74. doi: 10.1186/s12940-021-00756-5. |
| 28081369 | Derived | Alexander D, Northcross A, Wilson N, Dutta A, Pandya R, Ibigbami T, Adu D, Olamijulo J, Morhason-Bello O, Karrison T, Ojengbede O, Olopade CO. Randomized Controlled Ethanol Cookstove Intervention and Blood Pressure in Pregnant Nigerian Women. Am J Respir Crit Care Med. 2017 Jun 15;195(12):1629-1639. doi: 10.1164/rccm.201606-1177OC. |