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Change of device used for dual energy computed tomography with Xenon
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Demonstrate the feasibility of dual energy computed tomography using Krypton as a gaseous contrast media in order to study the in vivo ventilation.
Two different clinical situations will be tested :
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| oncologic patients | Experimental | Prediction of postoperative pulmonary function. Patients with an operable lung cancer: dual energy computed tomography with Krypton will be tested to estimate the postoperative FEV1 |
|
| lung transplant recipients | Experimental | Detection of BOS 6 months+ lung transplant recipients will be tested using dual energy computed tomography with Krypton, with acquisition in the end-inspiratory and end-expiratory phase, in search of regional air trapping. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Single source dual energy compted tomography (CT750HD, General Electric, USA) with Krypton as a gaseous contrast media | Radiation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Image quality on a qualitative 5 levels scale | 1 day of DECT ventilation imaging |
| Measure | Description | Time Frame |
|---|---|---|
| Radiation dose | 1 day of DECT ventilation imaging | |
| Image noise with measurement of signal to noise and contrast to noise ratios | 1 day of DECT ventilation imaging | |
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Inclusion criteria:
For oncologic patients :
For lung transplant recipients :
Exclusion criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Radiologie B - Nouvel Hôpital Civil - CHRU de Strasbourg | Strasbourg | 67091 Cedex | France |
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| Total examination time |
| 1 day of DECT ventilation imaging |