Esophageal Absorption in EoE

Esophageal Absorption in Eosinophilic Esophagitis

To determine how the esophagus in active and inactive stages of eosinophilic esophagitis tranmit fluids.

Inclusion Criteria:

• Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study
• endoscopy with esophageal and duodenal biopsies within two weeks of performance of this study
• Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study, and are now in histologic remission( <15phf) by the use of steroids or the six food elimination diet.
• Volunteers will be selected for not having any history of esophageal symptoms

Exclusion Criteria:

• Vulnerable populations, such as those with diminished mental acuity, will be excluded.
• Patients taking Nsaids within 48 hours of the d-xylose testing
• artificial sweeteners within 48 hours of the d-xylose testing
• History of IBD
• Currently smoking or history of smoking
• History of Celiac disease
• Bacterial overgrowth,
• motility disorders
• other diffuse small bowel diseases.