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The purpose of this study is to evaluate the long-term outcomes of Endoscopic Resection (ER) of superficial lesions of the Upper Gastrointestinal Tract(UGIT)
Endoscopic resection (ER) of superficial lesions of the upper gastrointestinal tract is a safe and effective surgery-sparing modality in experienced hands. It is often curative of dysplastic lesions and is associated with minimal complications and high patient acceptance (1-5). Westmead Hospital has accumulated a significant amount of experience in the removal of such lesions; however, there is limited research to document the long term outcomes of patients undergoing endoscopic resection.The purpose of this study is to evaluate the long-term outcomes of ER of superficial lesions of the UGIT.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endoscopic Mucosal Resection | Patients who are referred for Endoscopic Mucosal Resection of Upper Gastrointestinal Lesions will be included in this cohort. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endoscopic Mucosal Resection | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Observed procedural data | Number of Participants with Adverse Events as a Measure of Safety and Tolerability Outcomes | 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Analysis of the costs of this procedure compared to previous treatments | Perform cost-utility analyses comparing different treatment approaches for UGIT lesions | 14 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who have Upper Gastrointestinal Tract adenomas which are amendable to Endoscopic Mucosal Resection
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| Name | Affiliation | Role |
|---|---|---|
| Michael J Bourke, MBBS | Western Sydney Local Health District | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Westmead Endoscopy Unit | Westmead | New South Wales | 2145 | Australia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42128037 | Derived | Gupta S, Mandarino FV, Lam B, Gauci J, Kerrison C, McLeod D, Lee E, Burgess N, Bourke MJ. Long-Term Outcomes of Endoscopic Submucosal Dissection for Esophageal Squamous High-Grade Dysplasia and Early Squamous Cell Carcinoma in the West: Absolute vs Outside Criteria. Clin Gastroenterol Hepatol. 2026 May 12:S1542-3565(26)00354-X. doi: 10.1016/j.cgh.2026.04.030. Online ahead of print. |
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| ID | Term |
|---|---|
| D018253 | Adenoma, Villous |
| ID | Term |
|---|---|
| D000236 | Adenoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D000069916 | Endoscopic Mucosal Resection |
| ID | Term |
|---|---|
| D016099 | Endoscopy, Gastrointestinal |
| D016145 | Endoscopy, Digestive System |
| D003938 | Diagnostic Techniques, Digestive System |
| D019937 | Diagnostic Techniques and Procedures |
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| D003933 | Diagnosis |
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D019060 | Minimally Invasive Surgical Procedures |