Perioperative Neuroprotection of Stellate Ganglion Block

Preventive Effect of Stellate Ganglion Block on Cerebral Vasospasm in Patients Undergoing Aneurysm Surgery

To investigate whether stellate ganglion block is helpful to brain protection during cranial aneurysm surgery

The vasospasm after cranial aneurysm surgery have a higher incidence, but not have an ideal treatment method. At present, the medical treatment is very limited effect to prevent the perioperative cerebral ischemia.Stellate ganglion block （SGB）is an effective and well-tolerated approach to the treatment of CVS in various clinical settings.Resent study indicated that SGB has a protective effect on delayed cerebral vasospasm in an experimental rat model of subarachnoid hemorrhage.Therefore,we hypothesized that the preoperative SGB would be a effective treatment for improvement of vasospasm after cranial aneurysm surgery.

Inclusion Criteria:

• aneurysm subarachnoid hemorrhage patients scheduled for cranial aneurysm surgery，
• ASA grade：Ⅱ-Ⅲ，
• Hunt～Hess grade :Ⅰ-Ⅲ,
• have a informed consent.

Exclusion Criteria:

• history of mental illness，
• local infection who can't do stellate ganglion block，
• pregnant or lactating，
• nausea cancer or diabetes，
• participated the study or other related research in the last 30 days，
• unruptured aneurysms patients