NMES During the Day and Prior to Sleep

The Effect of Neuromuscular Electrical Stimulation on Post-prandial Protein Accretion During the Day and Prior to Sleep

In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and prior to sleep

In the present study, the effect of a bolus of intrinsically labeled milk directly after an hour of one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and immediately prior to sleep

Inclusion Criteria:

• Age 65-85 years
• Male
• 18.5 ≤ BMI ≤ 30.0

Exclusion Criteria:

• Type II diabetes
• All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery).
• Use of anticoagulants, blood diseases, allergy for lidocaine
• Use of NSAIDs (non-steroidal anti-inflammatory drugs) and acetylsalicylic acid
• Patients suffering from PKU (Phenylketonuria)
• Presence of implantable cardioverter defibrillator and/or pacemaker
• Performed regular resistance type exercise in the past 6 months
• Use of any tools to assist during walking (cane/ crutches/ walker)
• (Partial) foot/ leg amputation