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| Name | Class |
|---|---|
| Universiti Putra Malaysia | OTHER |
| IMU University, Malaysia | OTHER |
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This study will be comparing human body responses by the effects of diets cooked with NoveLin, virgin olive oil and RBD coconut oil.
NoveLin has high content of monounsaturate fatty acids - oleic acid (C18:1) which is the predominant fatty acid and in this study NoveLin is used as cooking fat in compare with olive oil. Olive oil is the world's most commonly eaten monounsaturated oil which contains 55 - 83% oleic acid. Consumption of olive oil gives numerous health benefits on lowering total and LDL cholesterol, reducing LDL cholesterol's, lowering blood clotting factors, and lowering blood pressure. Coconut oil is the richest source of medium chain fatty acid and it has greater than 90% of saturated fatty acid with dominant fatty acid of lauric acid (C12:0). RBD coconut oil is used as positive control in this study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test Fat P | Experimental | Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3. |
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| Test Fat Q | Experimental | Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3. |
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| Test Fat R | Experimental | Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| diets | Other | Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared. |
| Measure | Description | Time Frame |
|---|---|---|
| change in c-peptide level | week 0(baseline) and week 6 |
| Measure | Description | Time Frame |
|---|---|---|
| change in insulin resistance's markers | week 0(baseline) and week 6 | |
| change in inflammatory markers | week 0(baseline) and week 6 | |
| change in obesity markers |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Voon Phooi Tee, PhD | MPOB | Principal Investigator |
| Lee Sin Tien, BSc | UPM | Principal Investigator |
| Norhaizan Md Esa, PhD | UPM | Principal Investigator |
| Tony Ng Kock Wai, PhD | IMU | Principal Investigator |
| Verna Lee Kar Mun, PhD | IMU | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| MPOB | Kajang | Selangor | 43000 | Malaysia |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| D004032 | Diet |
| ID | Term |
|---|---|
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| week 0(baseline) and week 6 |
| change in lipid profile | week 0(baseline) and week 6 |
| change in physical characteristic (eg. BMI, body weight) | week 0(baseline) and week 6 |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |