Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort

Effect of Glycopyrrolate and Atropine as Adjuncts to Reversal of Non-Depolarizing Neuromuscular Blocking Agents on Postoperative Catheter-Related Bladder Discomfort

We want to evaluate the efficacy of the glycopyrrolate and atropine for the prevention of catheter-related bladder discomfort.

The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. The adjuncts to reversal agents such as glycopyrrolate and atropine are known to block the muscarinic receptor in different ways.

We want to evaluate the efficacy of the glycopyrrolate and atropine for the prevention of catheter-related bladder discomfort.

Inclusion Criteria:

• Patients scheduled for transurethral bladder excision under general anesthesia
• ASA I-III

Exclusion Criteria:

• Foley catheter less than 18 Fr.
• Patients with obstruction of urinary tract
• Patients with neurogenic bladder
• Patients with severe obesity
• Patients with neurologic disorder
• Patients with chronic pain
• Patients with allergic history to atropine or glycopyrrolate