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| ID | Type | Description | Link |
|---|---|---|---|
| CRBD_SNUH1 | Other Grant/Funding Number | Seoul National University of Hospital |
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To evaluate the efficacy of dexmedetomidine for the prevention of catheter-related bladder discomfort
After transurethral bladder resection, large-sized foley catheter have been used for drainage of urine and residual blood. Because of urinary catheterization, patients usually experiences catheter-related bladder discomfort defined as a burning sensation with an urge to void or discomfort in the supra-pubic region caused by catheter- related bladder irritation.
Dexmedetomidine is an alpha-2 antagonist and used as an analgesic agent. The investigators try to evaluate The efficacy of dexmedetomidine for the treatment of catheter-related bladder discomfort
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo group | Placebo Comparator | NS infusion will be done during surgery. |
|
| Dex group | Experimental | DEX infusion will be done during surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dex infusion | Drug | Dexmedetomidine will be injected (1 mcg/kg for 10 minutes and afterward 0.3 mcg/kg/hr) |
|
| Measure | Description | Time Frame |
|---|---|---|
| The number of patients with catheter-related bladder discomfort | catheter-related bladder discomfort at postoperative 1 hour was evaluated as none, mild, moderate, severe. The number of patients with mild, moderate, severe discomfort will be calculated and compared between groups. | at postoperative 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Catheter-related bladder discomfort | Catheter-related bladder discomfort will be evaluated as none, mild, moderate, severe at postoperative 0, 1, 6, 24 hours. | at postoperative 0, 1, 6, 24 hours |
| Pain at suprapubic area |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hyun-Chang Kim, MD | Contact | onidori1979@gmail.com | ||
| Hee-Pyong Park, Ph.D | Contact | hppark@snu.ac.kr |
| Name | Affiliation | Role |
|---|---|---|
| Hee-Pyoung Park | Seoul National University of Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Recruiting | Seoul | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25485879 | Derived | Kim HC, Lee YH, Jeon YT, Hwang JW, Lim YJ, Park JE, Park HP. The effect of intraoperative dexmedetomidine on postoperative catheter-related bladder discomfort in patients undergoing transurethral bladder tumour resection: A double-blind randomised study. Eur J Anaesthesiol. 2015 Sep;32(9):596-601. doi: 10.1097/EJA.0000000000000196. |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D009325 | Nausea |
| D014839 | Vomiting |
| D001145 | Arrhythmias, Cardiac |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012817 | Signs and Symptoms, Digestive |
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| NS infusion | Drug | Normal saline will be infused during surgery |
|
Pain at suprapubic area will be evaluated using NRS (0:none, 100:worst imaginable) at postoperative 0, 1, 6, 24 hours
| at postoperative 0, 1, 6, 24 hours |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |