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| Name | Class |
|---|---|
| Ministry of Health, Iraq | NETWORK |
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Although several studies have considered the relationship between infertility and semen super oxide radical scavengers levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on superoxide radical scavengers activity which are important in fertility of the individual has been reported.
The present study was conducted to study the effect of zinc supplementation on the quantitative and qualitative characteristics of semen along with superoxide radical scavengers activity in the seminal plasma of asthenospermic patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Zinc sulfate | Experimental | 60 subfertile (age 32.5±3.23 year) men with asthenozoospermia was treated with zinc sulfate, every participant took two capsules of zinc sulfate per day for three months (each one 220 mg). |
|
| Healthy control | No Intervention | 60 fertile (age 31.6±3.3 year) men, no treatment. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| zinc sulfate | Dietary Supplement | The subfertile group treated with zinc sulfate, every participant took two capsules of zinc sulfate per day for three months (each one 220 mg). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oxido-sensitive index level in spermatozoa and seminal plasma. | up to three months. |
| Measure | Description | Time Frame |
|---|---|---|
| Volume of semen. | up to three months. | |
| Xanthine oxidase activity in spermatozoa and seminal plasma. | up to three months. | |
| Catalase like activity in spermatozoa and seminal plasma. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mahmoud H. Hadwan, PhD | Babylon University/ Iraq | Principal Investigator |
| Lamia A. Almashhedy, PhD | Babylon University/ Iraq | Study Director |
| Abdulrrazaq S. Alsalman, PhD | Babylon University/ Iraq | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Babylon University | Hillah | Babylon | 51002 | Iraq |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26780395 | Derived | Hadwan MH, Almashhedy LA, Alsalman AR. Oral Zinc Supplementation Restores Superoxide Radical Scavengers to Normal Levels in Spermatozoa of Iraqi Asthenospermic Patients. Int J Vitam Nutr Res. 2015;85(3-4):165-73. doi: 10.1024/0300-9831/a000235. |
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| ID | Term |
|---|---|
| D053627 | Asthenozoospermia |
| ID | Term |
|---|---|
| D007248 | Infertility, Male |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D019287 | Zinc Sulfate |
| ID | Term |
|---|---|
| D013431 | Sulfates |
| D013464 | Sulfuric Acids |
| D013456 | Sulfur Acids |
| D013457 | Sulfur Compounds |
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| up to three months. |
| Superoxide dismutase activity in spermatozoa and seminal plasma. | up to three months. |
| Progressive sperm motility percentage. | up to three months |
| Total normal sperm count. | up to three months. |
| D007246 |
| Infertility |
| D052801 | Male Urogenital Diseases |
| D007287 |
| Inorganic Chemicals |
| D017967 | Zinc Compounds |