Brain Mechanisms Underlying the Effect of the Motilin Receptor Agonist Erythromycin on Hunger in Normal Weight Subjects | NCT02212821 | Trialant
CompletedInterventionalPhase 4Updated Nov 30, 2016
Brain Mechanisms Underlying the Effect of the Motilin Receptor Agonist Erythromycin on Hunger in Normal Weight Subjects
ClinicalTrials.gov ID
NCT02212821
Lead Sponsor
Universitaire Ziekenhuizen KU LeuvenOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Phase 4
Enrollment
14Actual
Last Update Posted
Nov 30, 2016Estimated
Start Date
Sep 2014
Primary Completion Date
Sep 2016Actual
Brief Summary
The purpose of this study is to investigate the role of erythromycin, a prokinetic agent, on hunger, and the brain mechanism lying behind it.
Healthy Volunteers
Erythromycin
Placebo
Ages Eligible for Study
Adult (18-64)
Sexes Eligible for Study
Female
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Female only.
Age > 18 and < 60.
Body Mass Index (BMI) of 19-25 kg/m2 (no weight change of more than 5 kg in the past three months).
Not known to have any chronic medical illness or illnesses affecting the gastrointestinal, cardiovascular, or nervous systems, chronic pain or psychiatric disorder.
If female not known to be pregnant.
Not known to have any past upper gastrointestinal surgery.
Exclusion Criteria:
Alcohol consumption > 7 drinks / week
Major depression and chronic health conditions except controlled hypertension