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| ID | Type | Description | Link |
|---|---|---|---|
| R01NS081710-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Neurological Disorders and Stroke (NINDS) | NIH |
| National Institutes of Health (NIH) | NIH |
| The Cleveland Clinic | OTHER |
| HDT Global |
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Upper limb amputation is a devastating injury that leaves many thousands of typically young and active individuals in the US to rely on artificial arms and hands to help restore their lost function. The investigators research is focused on helping these individuals to feel where their prosthetic limbs are moving without having to look at them by developing devices and approaches to provide sensory feedback of limb movement through the nerves that once served the missing limb.
In the investigators research the investigators seek to understand the organization and (function/operation) of sensory neural systems in order to develop methods for restoring function to injured populations. One of the primary focus areas of the investigators research is working to integrate physiologically relevant sensory feedback with prosthetic limbs. To this end the investigators employ a variety of approaches that interweave disciplines such as electrophysiology, psychophysics, biomedical engineering and cognition. The investigators research team is composed of an interconnected and communicative network of clinicians, engineers, and scientists. This helps us to provide pathways from basic science discoveries that can be used to address clinical needs with transition directly to patient care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Upper Extremity Amputee | Robust custom tactor to facilitate embodiment and proprioception |
| |
| Able Bodied | Bypass tactor |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tactor array | Device |
| ||
| Bypass Tactor |
| Measure | Description | Time Frame |
|---|---|---|
| Embodiment of the Prosthetic limb | Visual loading for fine motor tasks,questionnaires, and residual limb temperature will be assessed after 10 months of in home every day use of a custom robust tactor array for sensory feedback. | Ten months |
| Measure | Description | Time Frame |
|---|---|---|
| Investigate the perceptions of limb movement | Test how closely both targeted reinnervation amputees and able bodied study participants are able to interpret limb movement using the kinesthetic perceptual illusion and physiologically relevant kinesthetic feedback. | 6 months |
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Inclusion Criteria:
Amputee criteria:
Able Bodied participants:
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Amputees who have undergone targeted sensory reinnervation
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| Name | Affiliation | Role |
|---|---|---|
| Paul Marasco, PhD | Louis Stokes VA Medical Center, Cleveland Clinic Lerner Research Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rehabilitation Institute of Chicago | Chicago | Illinois | 60611 | United States | ||
| Louis Stokes VA Medical Center |
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| Label | URL |
|---|---|
| Related Info | View source |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Sep 22, 2017 | Jun 19, 2020 | ICF_000.pdf |
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| UNKNOWN |
| University of Alberta | OTHER |
| Shirley Ryan AbilityLab | OTHER |
| Defense Advanced Research Projects Agency | FED |
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| Cleveland |
| Ohio |
| 44106 |
| United States |
| Cleveland Clinic Lerner Research Institute | Cleveland | Ohio | 44195 | United States |
| University of Alberta Glenrose Rehabilitation Hospital | Edmonton | Alberta | T5B0B7 | Canada |