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The purpose of this study is to determine whether oxytocin influences emotional processing and learning of emotional and social stimuli.
An effect of OXT on emotion processing and anxiety has been broadly investigated in animal studies. However, in humans, effects seem more complex.
The rationale of the study is to examine direct effects of OXT to processing and learning of emotional and social values in humans.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oxytocin | Active Comparator | Oxytocin: Syntocinon-Spray, Novartis intranasal administration, 24 IU oxytocin; ; 3 puffs per nostril, each with 4 IU OXT |
|
| Placebo | Placebo Comparator | Placebo nasal spray |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxytocin | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Brain activity | fMRI | During emotion processing |
| Measure | Description | Time Frame |
|---|---|---|
| Psychophysiological response | Skin conductance response | During stimuli presentation |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D010121 | Oxytocin |
| ID | Term |
|---|---|
| D010909 | Pituitary Hormones, Posterior |
| D010907 | Pituitary Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
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| D006730 |
| Hormones, Hormone Substitutes, and Hormone Antagonists |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |