Dexmedetomidine Influence on the Level of Perioperative Blood Glucose and Insulin of Elderly Diabetes Patients

Dexmedetomidine is a kind of high selectivity alpha 2 agonists adrenaline, can inhibit the activity of sympathetic nerve, alleviate pain,and improve cardiovascular stability in the operation period. Dexmedetomidine have influence on perioperative stress response and immune function,but it is not clear.

Inclusion Criteria:

• Aged 60 to 80 years old;
• Type 2 diabetes;
• Not use insulin treatment;
• Onging general anesthesia surgery;
• Surgery time 1-3 hours

Exclusion Criteria:

• ASA classification > class II;
• Hypertension;
• Serious central nervous system diseases (acute stroke, uncontrolled seizures, -Severe dementia);
• Unstable angina and acute myocardial infarction;
• Allergy to investigational drug;
• Hepatic and renal dysfunction