Dexmedetomidine Affect Diabetic Patient's Glucose Metabolism

Perioperative Dexmedetomidine Affect Diabetic Patient's Glucose Metabolism

Dexmedetomidine's Sedative Effect on Diabetic Patient

Dexmedetomidine is a high selective α2 agonist,its sedative and analgesia feature is acclaimed. The pathogenesis of type 2 diabetes mellitus is associated with α2 excessive adrenaline receptors expression. This study is to evaluate whether the use of dexmedetomidine is helpful to Diabetic Patient through its antisympathetic effect

Inclusion Criteria:

• Age between 40 and 60
• Selective epigastrium surgery
• In

Exclusion Criteria:

• American Society of Anesthesiology (ASA) Physical Status>3
• Duration of operation >3 hours
• Hypovolemia,sinus bradycardia,atrioventricular block,severe hepatic and renal dysfunction,severe cardiac insufficiency