The Effects of a Ficus Carica in Subjects With Functional Constipation

Randomized, Double-Blind, Placebo-Controlled, Parallel Trial in Subjects With Functional Constipation, to Evaluate the Improvement in Constipation of Ficus Carica

The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Fig paste on functional constipation. The investigators measured colon transit time, frequency of defecation, defecation time, stool type, and abdominal discomfort.

Inclusion Criteria:

• age between 19 and 39 years,
• diagnosis of functional constipation by ROME III criteria,
• Colon transit time (CTT) ≥ 36 h,
• subjects giving written informed consent

Exclusion Criteria:

• allergic or hypersensitive response to any of the ingredients in the test products,
• having previous history or current disease of digestive system, cardiovascular system, endocrine system and neurological disorder,
• diagnosis of irritable bowel syndrome by ROME III criteria, etc,.