Effect of Flixweed and Fig on Irritable Bowel Syndrome With Predominant Constipation: a Single Blind Randomized Clinical Trial.

This study evaluates effect of Ficus carica and Descurainia Sophia on irritable bowel syndrome predominant constipation. one-third of patients will receive Ficus carica, another one-third will receive Descurainia Sophia and remained patients only will follow their regular diet for 4 months.

Inclusion Criteria:

• patients with irritable bowel syndrome predominant constipation

Exclusion Criteria:

• Subjects with significant cardiovascular, renal, hepatic, pulmonary, endocrine, metabolic, hematologic disorders,
• structural abnormalities of the gastrointestinal tract or
• diseases ⁄conditions that affected bowel transition,
• surgery,
• any prokinetic or laxative drug used during the past month,
• any medication that may affect gastrointestinal motility,
• other therapeutic dietary advice for IBS,
• used Fig or Flixweed during the last month,
• diarrhea,
• pregnancy or
• breast-feeding