This study is purposed to evaluate the efficacy and safety of YVOIRE® contour compared with Restylane SubQ™ injected into the anteromedial malar region.

Inclusion Criteria:

• Be male or female, 20-65 years of age

• Have anteromedial malar region volume loss as grade 2, 3, or 4 on the Mid Face Aesthetic Scale (MFAS) symmetrically on both sides

• Desire filler treatment to correct volume loss in the anteromedial malar region

• Accept the obligation not to receive any other mid facial procedures or treatments during the study

• Signed informed consent

• Those who fall under one of the following 3 cases

  1. Males or females who are surgically sterile
  2. Post-menopausal females who are above 45 years of age and 2 years after the last menstruation
  3. Fertile premenopausal females or males without having a surgical sterilization, who have agreed to use at least two contraception methods (one of the barrier methods must be included) for up to 14 days after the last treatment of the investigational device to avoid pregnancy

Exclusion Criteria:

• Have a history of hypertrophic scars or keloids
• Other criteria as identified in the protocol