Study of Skin Parameters in the PROOF Cohort

Study of Skin Parameters in the PROOF Cohort

This study aims to evaluate skin aging of an homogeneous population of 77 years old patient selected among the PROOF cohort who has been continuously investigated by cardiological examination.

Skin aging will be explored by macroscopic and microscopic evaluation. In particular, skin aging will be measured by an index of clinical aging (SCINEXA) and other complementary measures such as facial photos, standard and High Definition dermoscopy, elastography, sebumetry, in vivo and ex vivo confocal microscopy, and classical histological examinations.

Inclusion Criteria:

• included in the PROOF cohort
• Form consent signed

Exclusion Criteria:

• Past history of surgery and / or treatment of aesthetic medicine
• neurological disorders
• insulin-dependent diabetes,
• corticosteroids or retinoids (isotretinoin, ...) > 1 year