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This trial is a knowledge study utilizing skin measurement probes that are non-invasive instruments, with negligible risks for the subjects. No product will be studied.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 20-29 Years Old | |||
| 30-39 Years Old | |||
| 40-49 Years Old | |||
| 50-59 Years Old | |||
| 60-69 Years Old | |||
| 70-79 Years Old |
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| Measure | Description | Time Frame |
|---|---|---|
| Age-related changes in fine lines on the cheek | Measured using a 5 point photonumeric scale (Allergan Fine Lines scale) The scale range is 0 to 4, with 0 indicating no fine lines and 4 being the most severe fine lines (greater than 5 superficial lines with crosshatching). | 4 Months |
| Age-related changes in skin hydration on the cheek | Tissue dielectric constant measurement using MoistureMeter D (Delfin Technologies). Tissue dielectric constant is expressed as a unitless value that is directly proportional to the amount of water in the tissue. | 4 Months |
| Age-related changes in skin hydration on the cheek | Tissue dielectric constant measurement using a Corneometer (Courage & Khazaka). Tissue dielectric constant is expressed as a unitless value that is directly proportional to the amount of water in the tissue. | 4 Months |
| Age-related changes in skin barrier function on the cheek | Transepidermal water loss measurement using an AquaFlux AF100 (Biox Systems Ltd) | 4 Months |
| Age-related changes in skin radiance on the cheek | Measurement of light reflection using a Skin-Glossymeter GL200 (Courage & Khazaka) | 4 Months |
| Age-related changes in skin color on the cheek | Skin colorimetric measurement using a Spectrophotometer (Konica Minolta) | 4 Months |
| Age-related changes in skin melanin on the cheek |
| Measure | Description | Time Frame |
|---|---|---|
| Reproducibility and repeatability of the skin hydration measurement on the cheek | The reproducibility and repeatability of the tissue dielectric constant measurement using MoistureMeter D (Delfin Technologies) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the skin hydration measurement on the cheek |
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Inclusion Criteria:
Exclusion Criteria:
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100 female subjects will be included, with at least 10 subjects per age decade
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| Name | Affiliation | Role |
|---|---|---|
| Siham Rharbaoui, MD | DERMSCAN - Pharmascan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dermscan-Pharmascan | Villeurbanne | 69100 | France |
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Colorimetric measurement of skin melanin using a Mexameter MX18 (Courage & Khazaka) |
| 4 Months |
| Age-related changes in skin elasticity on the cheek and thigh | Skin elasticity measurement using a Cutometer (Courage & Khazaka), ElastiMeter (Delfin Technologies), and Dermal Torque Meter (Dia-Stron Limited) | 4 Months |
| Age-related changes in skin thickness on the cheek and thigh | Ultrasound imaging using a Dermascan Ultrasound (Cortex Technology) | 4 Months |
| Age-related changes in skin topography on the cheek and thigh | Skin topography imaged using a PRIMOS (Canfield Scientific) fringe projection imaging system. Output measurements from the images will include Ra (average roughness), Rz (average height of roughness), and Rt (maximum height of the roughness profile). | 4 Months |
| Age-related changes in skin topography on the cheek and thigh | Skin topography imaged using a DermaTOP (EOTECH) fringe projection imaging system. Output measurements from the images will include Ra (average roughness), Rz (average height of roughness), and Rt (maximum height of the roughness profile). | 4 Months |
| Age-related changes in skin density on the cheek and thigh | Ultrasound imaging using a Dermascan Ultrasound (Cortex Technology) | 4 Months |
The reproducibility and repeatability of the tissue dielectric constant measurement using a Corneometer (Courage & Khazaka) will be determined by repeating the measurement three times by two technicians |
| 4 Months |
| Reproducibility and repeatability of the skin barrier function measurement on the cheek | The reproducibility and repeatability of the Transepidermal water loss measurement using an AquaFlux AF100 (Biox Systems Ltd) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the skin radiance measurement on the cheek | The reproducibility and repeatability of the light reflection using a Skin-Glossymeter GL200 (Courage & Khazaka) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the skin color measurement on the cheek | The reproducibility and repeatability of the skin colorimetric measurement using a Spectrophotometer (Konica Minolta) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the skin melanin changes on the cheek | The reproducibility and repeatability of the colorimetric measurement of skin melanin using a Mexameter MX18 (Courage & Khazaka) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the changes in skin elasticity on the cheek and thigh | The reproducibility and repeatability of the skin elasticity measurement using a Cutometer (Courage & Khazaka), ElastiMeter (Delfin Technologies), and Dermal Torque Meter (Dia-Stron Limited) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the changes in skin thickness and density on the cheek and thigh | The reproducibility and repeatability of the measurement of ultrasound imaging using a Dermascan Ultrasound (Cortex Technology) will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the changes in skin topography on the cheek | The reproducibility and repeatability of the skin topographyusing a PRIMOS (Canfield Scientific) fringe projection imaging system will be determined by repeating the measurement three times by two technicians | 4 Months |
| Reproducibility and repeatability of the changes in skin topography on the cheek | The reproducibility and repeatability of the skin topography will be imaged using a DermaTOP (EOTECH) fringe projection imaging system and will be determined by repeating the measurement three times by two technicians | 4 Months |