To establish the performance of the Dexcom G4 Platinum with a Modified Algorithm continuous monitoring system when compared to a laboratory reference measurement.

A study to evaluate the performance of a modification to the G4 Platinum CGM system in adults with diabetes.

Inclusion Criteria:

• Ages 18 years or older
• Diagnosis of Type 1 diabetes or Type 2 diabetes on Intensive Insulin Therapy (ITT)
• Willing to participate in a clinic session

Exclusion Criteria:

• Use of Acetaminophen during study period
• Pregnancy
• Hematocrit (HCT) <35% (females) and 38% (males)
• Dialysis, history of cardiovascular disease, epilepsy, severe migraines in the past 6 months, adrenal disease, syncope, significant hypoglycemia unawareness, or a history of severe hypoglycemia within the last 6 months.
• Any condition that, in the opinion of the Investigator, would interfere with their participation in the study or pose and excessive risk to study staff.

Type 1 and Type 2 diabetes patients

7 days of continuous glucose monitoring system use.

AEs assessed for all participants enrolled into the study