Unknown statusInterventionalPhase 3Updated Mar 28, 2013
Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography | NCT02070679 | Trialant
CompletedInterventionalPhase 3Updated Jun 16, 2015
Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography
ClinicalTrials.gov ID
NCT02070679
Lead Sponsor
Urmia University of Medical SciencesOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Phase 3
Enrollment
284Actual
Last Update Posted
Jun 16, 2015Estimated
Start Date
Feb 2014
Primary Completion Date
May 2015Actual
Completion Date
Jun 2015Actual
Brief Summary
The purpose of this study is to evaluate the effect of vitamin E on preventing from incidence of contrast induced acute kidney injury (CI-AKI) in the patients who undergone coronary angiography.
Stable Angina
Unstable Angina
Non ST Segment Elevation Myocardial Infarction
Post MI
Vitamin E
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
All patients whon have either stable coronary artery disease (CAD) or recent acute coronary disease (ACS) and are scheduled for coronary angiography.
Patients who have eGFR ≤60 ml/min/1.73 m2
Exclusion Criteria:
Allergy to contrast media
Cardiogenic shock
Pulmonary edema
Overt cardiac failure or left ventricular ejection fraction ≤ 30%
Acute kidney injury
The history of receiving contrast media for any medical diagnostic or therapeutic procedures during previous 5 days
The history of dialysis
Being pregnant
Having recent acute myocardial infarction
Taking antioxidants and nephrotoxic drugs including NSAID and ACE-I on previous 2 days