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The purpose of this study is to evaluate the effects of a computerized working memory training program on substance abuse, psychosocial functioning, cognitive performance and psychiatric problems in adults with substance abuse and attention problems.
The primary aim of this study is to examine the effects of 5 weeks of computerized working memory training on substance abuse. Secondary aims are to explore whether effects are mediated by changes in executive functions and/or moderated by personality. Also, effects on measures of psychosocial functioning, depression, anxiety and attention will be explored. Follow-up assessment will be conducted at 6 months post training.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cogmed working memory training | Experimental | 30-40 minutes of Cogmed computerized working memory training 3-5 days a week for 5-8 weeks. Every training session consists of a set of visual- and verbal working memory tasks that are trained on during the session. |
|
| Treatment as usual | Active Comparator | Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment. After a 8 week period participants in this arm well be offered Cogmed working memory training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computerized Cogmed working memory training | Behavioral | Computerized working memory training with Cogmed QM software. The QM software consists of a set of verbal and visual working memory tasks which is trained for 25-40 minutes each session. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA). | Baseline and at 25 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale. | Baseline and at 25 weeks | |
| Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index. | Baseline and at 25 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rickard Ahlberg, doctoral student | Contact | rickard.ahlberg@orebroll.se | ||
| Kurt Skårberg, MD | Contact | kurt.skarberg@orebroll.se |
| Name | Affiliation | Role |
|---|---|---|
| Lars Kjellin, Docent | Örebro Läns Landsting | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Psychiatric Research Centre | Recruiting | Örebro | Örebro County | 701 16 | Sweden |
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| Treatment as usual | Behavioral | Treatment as usual can consist of medication, psychotherapy, counseling, and psychological assessment. |
|
| Change from baseline in Adult Self Report (ASR; ASEBA) Externalizing index. | Baseline and at 25 weeks |
| Change from baseline in Adult Self Report (ASR; ASEBA) Adaptive functioning scales. | Baseline and at 25 weeks |
| Change from baseline in Executive functioning measured with Behavior Rating Inventory of Executive Function-Adult (BRIEF-A). | Baseline and at 25 weeks |
| Change from baseline in verbal working memory measured with performance on Digit span. | Baseline and at 25 weeks |
| Change from baseline in visual working memory measured with performance on Span board. | Baseline and at 25 weeks |
| Change from baseline in focused attention measured with performance on Conners Continuous Performance Test-II (CCPT-II). | Baseline and at 25 weeks |
| Change from baseline in vigilance measured with performance on Conners Continuous Performance Test-II (CCPT-II). | Baseline and at 25 weeks |
| Change from baseline in reading speed measured with performance on Reading speed in Diagnostic Reading and Writing Test (DLS; Swedish version). | Baseline and at 25 weeks |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| D001008 | Anxiety Disorders |
| D003863 | Depression |
| D000987 | Antisocial Personality Disorder |
| D004410 | Dyslexia |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D010554 | Personality Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D000067559 | Specific Learning Disorder |
| D007859 | Learning Disabilities |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D065886 | Neurodevelopmental Disorders |
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| ID | Term |
|---|---|
| D013812 | Therapeutics |
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