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| ID | Type | Description | Link |
|---|---|---|---|
| 2010-020044-35 |
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Describing a pharmacokinetic model of 48-h sevoflurane sedation in obese ICU patients
Prospective clinical monocentric study in ICU with sedated ventilated obese patients with sevoflurane during 48 h with the AnaConda® system, establishing pharmacokinetic model of sévoflurane and its metabolites (hydroxyfluroisopropanol, fluoride)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sevoflurane | Experimental | Determination of plasmatic concentrations of sevoflurane at different times of a 48h sedation of sevoflurane in obese ICU patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sedation with sevoflurane during 48-hr in ICU | Drug |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Determination of plasmatic concentrations of sevoflurane before using AnaConda® system | at 5min, 60 min, 24 hrs and just before the end of sedation. |
| Measure | Description | Time Frame |
|---|---|---|
| Determination of plasmatic concentrations of HFIP and fluoride before using AnaConda® system | at 5min, 60 min, 24 hrs and just before the end of sedation. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sébastien PERBET | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Clermont-Ferrand | Clermont-Ferrand | 63003 | France |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D007362 | Intensive Care Units |
| ID | Term |
|---|---|
| D006757 | Hospital Units |
| D006268 | Health Facilities |
| D005159 | Health Care Facilities Workforce and Services |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |