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The study will quantitatively evaluate the metabolic response of normal weight and obese subjects to three high-fat meals differing in caloric dose by analysing the postprandial blood transcriptome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| normal weight subjects | Experimental |
| |
| obese subjects | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| high-fat meal A | Other |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| blood cell transkriptome/ gene-expression |
| 0h, 2h, 4h, 6h |
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Inclusion Criteria for normal weight subjects:
Inclusion Criteria for obese subjects:
Exclusion Criteria for both groups:
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| Name | Affiliation | Role |
|---|---|---|
| Guy Vergeres, PhD | Agroscope Liebefeld-Posieux Research Station ALP | Principal Investigator |
| Doreen Gille, M.Sc. | Agroscope Liebefeld-Posieux Research Station ALP | Study Director |
| Kurt Laederach, MD | Inselspital University of Berne | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Agroscope | Bern | Canton of Bern | CH-3003 | Switzerland | ||
| University Hospital Inselspital Berne |
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| high-fat meal B | Other |
|
|
| high-fat meal C | Other |
|
|
| Bern |
| Canton of Bern |
| CH-3010 |
| Switzerland |
| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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