Metabolic Response to Fat and Glucose

Metabolic Response to Fat and Glucose

The study will compare plasma and urine post-prandial metabolomics after fat and glucose oral load according to lifestyle factors.

The metabolic response in plasma and urine, pre- and post-load tests in people with specific dietary lifestyles will be tested. This project will focus on fat and glucose induced changes of targeted metabolic pathways that have been related to diabetes and obesity risk.

Inclusion Criteria:

• Healthy volunteers
• On a stable dietary habits

Exclusion Criteria:

• Pregnancy
• Malabsorption disorders
• Present or former cancer
• Any oral medication that affect glucose or fat absorptions
• Cholesterol lowering drugs (i.e. Statins)
• other drugs: fibrates, MTX, or vitamin supplements
• Diabetes (type 1 and type 2)
• Alcoholism
• Weight losing diet during the last 4 months
• Liver diseases
• Renal dysfunction
• Gastric resection.