Metabolic Syndrome and Male Infertility

Relationship Between Sperm Parameters and Metabolic Syndrome in a Infertile Couple Partner Man

Multidisciplinary, multicentric, cross-sectional study on men in infertile couples who conduct their sperm test through their diagnosis of infertility

Assessment of sperm parameters and metabolic syndrome relations in men attending a Reproductive Biomedicine centre for an infertility of their couple.

Secondary objectives are to study relationship between sperm parameters and:

• adiposity and insulin resistance
• inflammation
• oxydative stress in blood and semen
• hormonal status Innovative parameters will also be assessed to determine the quality of semen (length of fingers, wrist circumference and epigenetics studies)

Inclusion Criteria:

• 18 to 45 years-old man
• man consulting for primary or secondary infertility, with or without earlier notion of paternity
• patient insured with a social security scheme
• patient who have had a prior medical consultation
• patient who have done informed and written consent to participate in the research study

Exclusion Criteria:

• patient with problems understanding French

• patient smoking more than two-pack-a-day

• patient monitoring for viral risk.

• man with an unidiopathic infertility which may be explained by:

  1) identifiable factors in direct questioning at the sperm analysis:

• exposure to toxic products

• infectious disease history

• pathological anatomical background 2) factors identified at the etiologic investigation: cytogenetic and genetic