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| Name | Class |
|---|---|
| University of Zurich | OTHER |
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It was shown by some researchers that dietary nitrate such as beet root juice can lower oxygen consumption in men and act as a performance enhancing supplement.
It was not shown, what the optimal dosage is and if there is any difference in oxygen consumption comparing beet root juice and inorganic nitrate.
Therefore, the aim of the study is to conduct a study ingesting different sodium nitrate and beet root juice dosages. We would measure nitrate and nitrite concentrations in the blood at different time points and the subjects have to perform an exercise test measuring oxygen consumption 3 hours after the ingestion of nitrate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sodium Nitrate 12mmol | Active Comparator | Ingestion of a solution of inorganic nitrate, dosage: 12mmol |
|
| sodium Nitrate (6mmol) | Active Comparator | ingestion of inorganic nitrate (6mmol solution) |
|
| sodium nitrate 3mmol | Active Comparator | ingestion of inorganic nitrate (3mmol solution) |
|
| sodium nitrate (0mmol) | Active Comparator | Ingestion of water as a placebo |
|
| Beetroot juice (12mmol) | Active Comparator | ingestion of 170ml of concentrated beetroot juice (12mmol) |
|
| beetroot juice (6mmol) | Active Comparator | ingestion of 85ml concentrated beetroot juice (6mmol) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sodium nitrate | Dietary Supplement | Ingestion of 3mmol, 6mmol and 12mmol sodium nitrate |
|
| Measure | Description | Time Frame |
|---|---|---|
| oxygen consumption | Oxygen consumption during exercise protocol | 30min |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | every hour, blood pressure is measured. | 6 hours |
| oxygen saturation | every hour oxygen saturation is measured. | 6 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Claudio Perret, Dr. sc. nat. | Sportmedizin Nottwil | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Swiss Paraplegic Centre | Nottwil | Canton of Lucerne | 6207 | Switzerland |
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| ID | Term |
|---|---|
| C031618 | sodium nitrate |
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|
| Beetroot juice (3mmol) | Active Comparator | Ingestion of 42.5ml of concentrated beetroot juice (3mmol) |
|
|
| Beetroot juice | Dietary Supplement | concentrated beetroot juice (dosage 3mmol, 6mmol and 12mmol) |
|
|
| Rating of perceived exertion (RPE) | RPE is measured after the low-intensity exercise performance and after the submaximal exercise performance. | during the 7 weeks of study phase |
| Heart rate | Heart rate is measured before the ingestion, before the exercise test and during the exercise test. resting heart rate is additionally measured every hours after the intake of dietary/inorganic nitrate. | during the 7 weeks of study phase |
| Nitrate and nitrite concentration | every hour for the six hours after the ingestion of dietary/inorganic nitrate, nitrate and nitrite concentration in the blood is analyzed. | 6 hours |