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The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Beetroot Juice | Experimental |
| |
| Beetroot Juice no Nitrate | Active Comparator |
| |
| Sodium Nitrate | Active Comparator |
| |
| Control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sodium Nitrate | Dietary Supplement | 70ml sodium nitrate, matched for nitrate concentration in Beetroot Juice arm |
|
| Measure | Description | Time Frame |
|---|---|---|
| Time to Exhaustion | A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Gordon Fisher, PhD | University of Alabama at Birmingham | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | United States |
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| Beetroot Juice no Nitrate | Dietary Supplement | 70ml Concentrated Beetroot Juice with nitrate removed |
|
| Beetroot Juice | Dietary Supplement | 70ml Concentrated Beetroot Juice |
|
| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| D009765 | Obesity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| C031618 | sodium nitrate |
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