Transcranial Direct Current Stimulation Aided Rehabilitation of Gait in Subacute Stroke

The purpose of this study is to determine if transcranial direct current stimulation (tDCS)applied over the lower extremity motor cortex in conjunction with treadmill training is effective for improving gait in patients with subacute stroke and to evaluate the effect and predictive value of a single session of anodal tDCS.

Inclusion Criteria:

• Age ≥ 18 years
• Onset of stroke less than 14 days
• First ischemic stroke causing lower limb weakness (MRC score ≤4 in knee extensors) and gait impairment

Exclusion Criteria:

• Contraindications to MRI or TMS
• Other neurological disorders
• Significant somatic or psychiatric disorders
• History of seizures
• Language or cognitive disorders prohibiting participation