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16 acute stroke patients will be split into 2 groups. One group will receive the real treatment (anodal tDCS) and one group sham.
Subjects will receive, in addition to conventional rehabilitation, 2mA for 20 mins of their attributed tDCS, 5 times a week.
Evaluations will take place before the first stimulation period (48h post stroke), after 1, 2, 3 and 4 weeks.
The evaluations are the Four Square Step Test, the Berg Balance Scale, the Postural Assessment Scale For Stroke, the Trunk Impairment Scale, the Time Up & Go and the 10 meter walking test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment | Active Comparator | Anode placed over the affected primary motor cortex, cathode over contralateral supra orbital area. 2 mA, 20min stimulation, 5 days a week for 4 weeks |
|
| Placebo | Placebo Comparator | Anode montage but current is ramped up over 15 secondes, then ramped down. 2 mA, 20min stimulation, 5 days a week for 4 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anodal Transcranial Direct Current Stimulation | Device | Subjects received a micro-current through their scalp to induce cortical and subcortical changes |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes Four Square Step Test | The subject is required to sequentially step over four canes set-up in a cross configuration on the ground. The faster the score, the better the patients balance and coordination. | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
| Changes Berg Balance Scale | Balance Test. Minimum score is 0, maximum 36. The higher the score, the better the balance. | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
| Changes Postural Assessment Scale For Stroke | alance Test. Minimum score is 0, maximum 56. The higher the score, the better the balance. | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
| Changes Trunk Impairment Scale | alance Test. Minimum score is 0, maximum 23. The higher the score, the better the balance. | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
| Changes Time Up & Go | To determine fall risk and measure the progress of balance, sit to stand and walking. The faster, the better. | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
| Changes 10 meter walking test | 10 meter walking test, the faster the better | Pre Stimulation (48 hours post stroke), Week 1, Week 2, Week 3, Week 4 |
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Inclusion Criteria:
Exclusion Criteria:
• One Yes on the medium and high risk sections of the TSST (Bornheim et al.,2019)
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stephen Bornheim, Msc | Contact | 003243662193 | stephen.bornheim@uliege.be |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Liege Univeristy Hospital | Recruiting | Liège | 4000 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30431445 | Background | Bornheim S, Croisier JL, Maquet P, Kaux JF. Proposal of a New Transcranial Direct Current Stimulation Safety Screening Tool. Am J Phys Med Rehabil. 2019 Jul;98(7):e77-e78. doi: 10.1097/PHM.0000000000001096. No abstract available. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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One group receives anodal tDCS, one placebo
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|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |