Prevention of Atrial Fibrillation by Optimized Overdrive Stimulation

Prevention of Atrial Fibrillation by Optimized Overdrive Stimulation

Evaluation of dynamic Atrial Overdrive Stimulation using the AF Suppression Algorithm to prevent atrial tachyarrhythmias in patients with more than 2% Auto Mode Switch Episodes with optimized pacemaker programming.

Hypothesis:

Dynamic atrial Overdrive (AF Suppression) reduces AT/AF Burden by 30% as compared to programming DDDR-(60) without AF Suppression when all other parameters are optimized.

Atrial Fibrillation is the most common Heart Rhythm Disorder requiring therapy.

Inclusion Criteria:

• indication for dual chamber pacemaker
• documented paroxysmal or persistent Atrial Fibrillation
• P-wave >1.0 mV in Sinus Rhythm or sufficient detection of AFib
• stable antyarrhythmic therapy
• age >= 19 years
• written informed consent
• implantation of a Identity DR 5370/5376 or later
• bipolar atrial lead

Exclusion Criteria:

• permanent AFib
• reversible etiology of AFib
• HYHA II or IV
• Coronary Artery disease with stable angina pectoris
• implanted ICD or planned implantation of a ICD
• cardiac surgery within the last 6 months or planned within 12 months
• live expectancy < 12 months
• pregnancy