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The project will specifically focus on the examination of the influence of substantial weight loss due to bariatric surgery on brain functions. Our hypothesis is that substantial weight loss after Bariatric Surgery (BS) is also accompanied by changes in the balance of reward and inhibitory networks in diabetic subjects. Therefore the investigators will conduct a functional magnetic resonance imaging (fMRI) study investigating functional measures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| pre bariatric surgery | |||
| post bariatric surgery |
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| Measure | Description | Time Frame |
|---|---|---|
| Differential brain functions | brain functions will be measured by blood oxygen level dependent effects | at least 6 months after bariatric surgery (experimental group) |
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| Measure | Description | Time Frame |
|---|---|---|
| Behavioral measurements | eating behavior | pre surgery (group 1) and at least 6 months after surgery |
Inclusion Criteria:
Exclusion Criteria:
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volunteers pre and post bariatric surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Clinic of Tuebingen, MEG Center | Tübingen | 72076 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27293200 | Derived | Frank S, Heinze JM, Fritsche A, Linder K, von Feilitzsch M, Konigsrainer A, Haring HU, Veit R, Preissl H. Neuronal Food Reward Activity in Patients With Type 2 Diabetes With Improved Glycemic Control After Bariatric Surgery. Diabetes Care. 2016 Aug;39(8):1311-7. doi: 10.2337/dc16-0094. Epub 2016 Jun 12. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |