Natural IVF study patients will undergo an IVF cycle with trigger shots of Lupron & hCG. Patients will not be given any other stimulating medications during the cycle. They will have 2 uterine aspirations and an endometrial biopsy at designated times. The first uterine aspiration will be randomized to one of four days (day before retrieval, day of retrieval, day after retrieval or 2 days after retrieval). The second uterine aspiration and endometrial biopsy will be performed 6 days after retrieval. Any embryo(s) obtained will be biopsied for Comprehensive Chromosome Screening (CCS) and frozen for use in a subsequent thaw cycle.

Inclusion Criteria:

• Ovulatory cycles every 39 days or less (natural cycle IVF cannot be performed in someone who does not have cycles)
• Must be RMANJ patient and have completed all diagnostic screening at one of our RMANJ locations. All diagnostic screening is NOT covered under the study and must be completed prior to being allowed to start the study cycle.

Exclusion Criteria:

• Prior enrollment/attempt in this study
• Requirement for surgical sperm extraction
• Inability to assess ovaries via transvaginal ultrasound
• Inability to tolerate vaginal examination

Infertile patients