The Effects of Administration of Combined Docosahexaenoic Acid and Vitamin E Supplements on Spermatogram and Seminal Plasma Oxidative Stress in Infertile Men With Asthenozoospermia

Since docosahexaenoic acid (DHA) level in sperm membrane has been shown to be decreased in asthenozoospermic men, the investigators hypothesized that DHA supplementation may improve it. Furthermore, the investigators added vitamin E to it to protect its unsaturated bonds which are susceptible to oxidation and production of free oxygen radicals.

Inclusion criteria:

• Willing to participate in the study and filling out the informed consent form
• should be infertile (no conception after 12 months intercourse without any contraception)
• age 20-45 y.o, idiopathic asthenospermia according to WHO criteria
• normal hormonal profile

Exclusion criteria:

• any infection in genitourinary (GU) tract
• any anatomical abnormality in GU tract
• any chronic disease during last 3 months
• any surgery in GU tract
• consumption of omega-3 fatty acids and/or vitamin E supplements during last 3 months