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| Name | Class |
|---|---|
| University of Barcelona | OTHER |
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The aim of this study is evaluated the effect of dietetic supplementation with DHA on human sperm quality, antioxidant capacity and sperm DNA damage.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sunflower oil | Placebo Comparator |
| |
| Docosahexanoic acid | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sunflower oil | Dietary Supplement | 1500 mg sunflower/day for 10 weeks |
| |
| Measure | Description | Time Frame |
|---|---|---|
| sperm concentration | million of spermatozoa per milimitre | 5 weeks |
| Sperm motility | Percentage of motile sperm. | 5 weeks |
| Sperm morphology | Percentage of sperm with normal morphology | 5 weeks |
| Total capacity antioxidant | Total antioxidant capacity (TAC)is a colorimetric assay that measure the combined antioxidant activities of all its non enzymatic constituents in seminal plasma. | 5 weeks |
| Sperm DNA damage. | DNA fragmentation analysis was evaluated by TUNEL test and measured by flow cytometry | 5 weeks |
| Fatty acids measure. | Fatty acid analysis in seminal plasma and spermatozoa were evaluated by gas chromatography.The percentage of each fatty acid class was expressed as percentage of total fatty acids. | 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Sperm in ejaculate | Million of spermatozoa in eyaculate. | 5 weeks |
| Volume of ejaculate. | Eyaculated milliliters. | 5 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Martinez Soto, Juan Carlos | IVI Murcia | Principal Investigator |
| Landeras Gutierrez, Jose | IVI Murcia | Study Director |
| Nicolas Arnau, Maria | IVI Murcia | Study Chair |
| Fernandez Olmedilla, Laura | IVI Murcia | Study Chair |
| Albero Pilar | IVI Murcia | Study Chair |
| Domingo JC | University of Barcelona | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Valenciano de infertilidad | Murcia | Murcia | 30007 | Spain |
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| ID | Term |
|---|---|
| D000074242 | Sunflower Oil |
| ID | Term |
|---|---|
| D010938 | Plant Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
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| Docosahexanoic acid |
| Dietary Supplement |
1500mg/day for 10 weeks |
|
| Sperm viability | Porcentage of sperm whitout membrane damage | 5 weeks |