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| ID | Type | Description | Link |
|---|---|---|---|
| R01DC011287 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Children's Hospital of Philadelphia | OTHER |
| University of Pennsylvania | OTHER |
| National Institute on Deafness and Other Communication Disorders (NIDCD) | NIH |
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This proposal describes a pilot study aimed at determining whether genetic variations in taste receptors determine differential taste tolerability of pediatric medications.
This is a cross-sectional call-back study of taste perception and the relationship between taste perception and taste receptor genotype.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women |
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| Measure | Description | Time Frame |
|---|---|---|
| Psychophysical data for taste solutions | Primary outcome variables are intensity ratings of pediatric medications as well as a variety of generally recognized as safe bitter and non-bitter compounds. | 1-2 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Maternal practices and perceptions of medication use | Secondary outcome variables include questions related to maternal practices and perceptions of medication use and compliance of their children. | 1-2 hours |
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Inclusion Criteria:
Exclusion Criteria:
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One hundred women who were previously enrolled in the study entitled "Efficacy of Bitter Blockers on Taste Acceptance in Pediatric Populations," Protocol #809789; will be recruited for the current study
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| Name | Affiliation | Role |
|---|---|---|
| Julie A. Mennella, PhD | Monell Chemical Senses Center | Principal Investigator |
| Elizabeth Lowenthal, MD MSCE | University of Pennsylvania | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Monell Chemical Senses Center | Philadelphia | Pennsylvania | 19104 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28923290 | Derived | Mennella JA, Mathew PS, Lowenthal ED. Use of Adult Sensory Panel to Study Individual Differences in the Palatability of a Pediatric HIV Treatment Drug. Clin Ther. 2017 Oct;39(10):2038-2048. doi: 10.1016/j.clinthera.2017.08.012. Epub 2017 Sep 18. |
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Saliva