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| ID | Type | Description | Link |
|---|---|---|---|
| (1)2009R50040 (2)LY12H02005 | Other Grant/Funding Number | (1) Foundation of Science and Technology Department of Zhejiang (2)Zhejiang Provincial Natural Science Foundation |
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The purpose of this study is to determine whether the postoperative insulin resistance and cytokine release would be attenuated in laparoscopic compared with open liver resection.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| laparoscopic liver resection | Procedure |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative insulin resistance calculated by serum insulin and blood glucose | At baseline prior to surgery, and 3hr, 12hr, 24hr, 72hrs after operation, blood glucose and insulin was measured. Insulin resistance is assessed by the HOMAIR(homeostatic model assessment of insulin resistance) score which is calculated through the mathematic formula: HOMAIR= FI ×FG/22.5, where FI= fasting serum insulin(μU/mL), FG= fasting plasma glucose (mmol/L), and 22.5 is a constant. | within the first 72hrs after operation |
| Measure | Description | Time Frame |
|---|---|---|
| cytokine changement including IL-1β, IFN-γ, IL-4 and IL-10 before and after operation | At baseline before operation and 0, 3hr, 12hr, 24hr, D3, D5 after operation, duplicated samples were drawn to analyze serum IL-1β, IFN-γ, IL-4 and IL-10. | within 5 days after operation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University | Hangzhou | Zhejiang | 310016 | China |
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| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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