There is a claim that creatine supplementation might affect kidney function, especially in those consuming a high-protein diet. The aim of this study was to investigate the effects of creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet.

Inclusion Criteria:

• participation in recreational resistance training
• consumption of a high-protein diet (≥ 1.2 g/Kg/d)

Exclusion Criteria:

• vegetarian diet
• use of creatine supplements in the past 6 months
• chronic kidney disease
• use of anabolic steroids.