Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy levels.
One of the factors that is potentially important in response inhibition is caffeine.
The aim is to assess the direct effects of caffeine on response inhibition, using a No Go/Go-task. We will also assess whether the presentation of food cues, i.e. as words or as pictures, modulate response inhibition different in restrained vs. non-restrained eaters.
In a blinded, randomized cross-over design, participants will receive either a capsule with caffeine or placebo at two separate occasions whereupon study tasks will be performed.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Caffeine | Experimental | Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test. |
|
| Placebo | Placebo Comparator | Administration of placebo (one gelatin capsule containing starch) with subsequent cognitive tasks and food test. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Caffeine | Drug | Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Inhibition control | Measurement inhibition control via a computer test (NoGo-Go task. | 20 min |
| Measure | Description | Time Frame |
|---|---|---|
| Food test | Measure of participants food intake. | 20 min |
| Measure | Description | Time Frame |
|---|---|---|
| Blood sample | Blood glucose assessment in order to confirm fasted condition prior to study experiments. | 5 min (1 sample) |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Pleunie Hogenkamp, PhD | Uppsala University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Uppsala University | Uppsala | 75319 | Sweden |
Not provided
| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D001522 | Behavior, Animal |
| D001519 | Behavior |
| D050177 | Overweight |
| D044343 | Overnutrition |
Not provided
Not provided
| ID | Term |
|---|---|
| D002110 | Caffeine |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Placebo | Drug | Administration of placebo with subsequent cognitive tasks and food test. |
|
| D009748 |
| Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D011687 |
| Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |