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The main aim of this study is to determine how common undiagnosed obstructive sleep apnoea is in individuals with intermittent claudication.
In patients with peripheral artery disease (PAD), exercise induced limb ischemia (claudication) which limits walking capacity. Symptoms are due to pain at hip and/or buttock. Couple of origins may induce this pain such as vascular, cardiac, respiratory, musculoskeletal, neurologic, hematologic etc. The rate of associated respiratory pathology to patients with lower extremity artery disease (LEAD) is around 15%. The intolerance to walk could be link to an exercise hypoxia which appears with lower limb pain with or without associated dyspnea. The exercise hypoxemia becomes a diagnostic for an intermittent vascular claudication. Tests which are performed to diagnose an intermittent claudication are the Ankle to Brachial Systolic pressure Index (ABI), the echo-Doppler of lower limb arteries and the walking test on a treadmill associated to a measurement of the distal and chest transcutaneous oxygen pressure (tcpO2).
Thus, the purpose of the present research is to determine the prevalence of obstructive sleep apnoea in patient with PAD.
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| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of an Apnea hyponea index > 15 | Recording of sleep with the RESMED (Apnealink) system | up to 2 months after inclusion |
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Inclusion Criteria:
Exclusion Criteria:
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men or women over 18 years old with an Intermitent claudication.
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| Name | Affiliation | Role |
|---|---|---|
| Guillaume Mahe, MD; PhD | University Hospital in Angers | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University hospital | Angers | 49933 | France |
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| ID | Term |
|---|---|
| D012891 | Sleep Apnea Syndromes |
| D020181 | Sleep Apnea, Obstructive |
| D007383 | Intermittent Claudication |
| D012120 | Respiration Disorders |
| D058729 | Peripheral Arterial Disease |
| ID | Term |
|---|---|
| D001049 | Apnea |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
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| D012893 |
| Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D016491 | Peripheral Vascular Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D050197 | Atherosclerosis |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |