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| Name | Class |
|---|---|
| Pediatric Orthopaedic Society of North America | OTHER |
| University of Pennsylvania | OTHER |
| Tennessee Orthopedic Alliance | OTHER |
| Children's Hospital Medical Center, Cincinnati |
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The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for stable forms of juvenile osteochondritis dissecans (JOCD) lesions. This study also aims to better define the natural history of this condition in its most commonly identified pathological state (as a stable lesion) following surgical intervention by determining the rate of radiographic healing and any need for secondary surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Retro-articular drilling | Active Comparator | Retro-articular drilling goes through the cortical margin of the affected condyle, thereby sparing the articular surface and physes. |
|
| Trans-articular drilling | Active Comparator | Trans-articular drilling penetrates the articular cartilage through multiple sites to create subchondral penetrations. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Retro-articular drilling | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Physical functioning measured by the Pedi-IKDC (International Knee Documentation Committee) total score | One year post-surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Activity level as measured by the Marx Activity Scale | One year post-surgery | |
| Physical functioning as measured by the Pedi-IKDC total score | Two years post-surgery | |
| Measure | Description | Time Frame |
|---|---|---|
| Surgical complications | Inadvertent displacement of OCD fragment; damage to articular cartilage and physes | 1 week to 1 year post-surgery |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Benton Heyworth, M.D. | Boston Children's Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaiser Permanente Los Angeles | Los Angeles | California | 90027 | United States | ||
| Rady Children's Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37039536 | Derived | Heyworth BE, Ganley TJ, Liotta ES, Hergott KA, Miller PE, Wall EJ, Myer GD, Nissen CW, Edmonds EW, Lyon RM, Chambers HG, Milewski MD, Green DW, Weiss JM, Wright RW, Polousky JD, Nepple JJ, Carey JL, Kocher MS; ROCK Group; Shea KG. Transarticular Versus Retroarticular Drilling of Stable Osteochondritis Dissecans of the Knee: A Prospective Multicenter Randomized Controlled Trial by the ROCK Group. Am J Sports Med. 2023 May;51(6):1392-1402. doi: 10.1177/03635465231165290. Epub 2023 Apr 11. |
| Label | URL |
|---|---|
| Research in OsteoChondritis of the Knee, OCD Study Group of North America | View source |
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| OTHER |
| Children's Hospital and Health System Foundation, Wisconsin | OTHER |
| Washington University School of Medicine | OTHER |
| The Hospital for Sick Children | OTHER |
| Children's Hospital of Philadelphia | OTHER |
| Kaiser Permanente | OTHER |
| Rady Children's Hospital, San Diego | OTHER |
| St. Luke's Children's Hospital | OTHER |
| Medical College of Wisconsin | OTHER |
| Connecticut Children's Medical Center | OTHER |
| Hospital for Special Surgery, New York | OTHER |
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|
|
| Trans-articular drilling | Procedure |
|
|
|
| Time to lesion healing |
Lesion healing will be assessed by x-ray at multiple time points |
| 3 months to 2 years post-surgery |
| San Diego |
| California |
| 92123 |
| United States |
| Rocky Mountain Hospital for Children | Centennial | Colorado | 80112 | United States |
| Connecticut Children's Medical Center | Farmington | Connecticut | 06032 | United States |
| St. Luke's Children's Hospital | Boise | Idaho | 83702 | United States |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | United States |
| Washington University School of Medicine | St Louis | Missouri | 63110 | United States |
| Hospital for Special Surgery | New York | New York | 10021 | United States |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | United States |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | United States |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States |
| Tennessee Orthopaedic Alliance | Nashville | Tennessee | 37205 | United States |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53201 | United States |
| The Hospital for Sick Children | Toronto | Ontario | M5G 1X8 | Canada |
| ID | Term |
|---|---|
| D010008 | Osteochondritis Dissecans |
| ID | Term |
|---|---|
| D010007 | Osteochondritis |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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