Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice

Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice: A Phase III, Randomized, Controlled, Single Center Study.

Patients with the lower malignant obstructive jaundice planned to do the pancreaticoduodenectomy, receiving preoperative biliary drainage or early surgery (without preoperative biliary drainage), both groups has the similar surgical morbidity, no statistics significance.

Patients with the lower malignant obstructive jaundice divided into two groups:early surgery, preoperative biliary drainage + surgery.

Inclusion Criteria:

• Patients with the lower malignant obstructive jaundice
• Total bilirubin: 150-350 umol/L

Exclusion Criteria:

• age less than 18
• emergency operation
• biliary tract stent placed
• past history of operation on pancreas
• intraoperative unresectable tumor with pancreaticoduodenectomy
• unresectable tumor or potential resectable tumor with pancreaticoduodenectomy